www.biloxi.ms.us Biloxi ( /bəˈlʌksi/ bə-LUK-see) is a city in Harrison County, Mississippi. The 2010 census recorded the population as 44,054. Along with the adjoining city of Gulfport, Biloxi is a county seat of Harrison County. The city is part of the Gulfport-Biloxi metropolitan area and the Gulfport-Biloxi-Pascagoula, Mississippi Combined Statistical Area. Pre-Katrina, Biloxi was the third largest city in Mississippi; but with its population losses following that storm, Hattiesburg now has that distinction. Also, in the 2010 census, Southaven is shown as the fourth largest city, so Biloxi is now ranked fifth in the state. The beachfront of Biloxi lies directly on the Mississippi Sound, with barrier islands scattered off the coast and into the Gulf of Mexico. Keesler Air Force Base lies within the city and is home to the 81st Training Wing and the 403d Wing of the U.S. Air Force Reserve.